%0 Journal Article
%T A influ¨ºncia do gen¨®tipo da ECA sobre a aptid£¿o cardiovascular de jovens do sexo masculino moderadamente ativos
%A Almeida
%A Jeeser Alves
%A Boullosa
%A Daniel Alexandre
%A Pardono
%A Emerson
%A Lima
%A Ricardo Moreno
%A Morais
%A Pamella Karoline
%A Denadai
%A Benedito S¨¦rgio
%A Souza
%A Vin¨ªcius Carolino
%A N¨®brega
%A Ot¨¢vio Toledo
%A Campbell
%A Carmem Silvia Grubert
%A Sim£¿es
%A Herbert Gustavo
%J Arquivos Brasileiros de Cardiologia
%D 2012
%I Sociedade Brasileira de Cardiologia - SBC
%R 10.1590/S0066-782X2012005000029
%X background: the angiotensin i-converting enzyme gene (ace gene) has been broadly studied as for cardiorespiratory fitness phenotypes, but the association of the ace genotype to middle-distance running has been poorly investigated. objective: this study investigated the possible influence of angiotensin-converting enzyme (ace) genotype (i/d) on cardiovascular fitness and middle-distance running performance of brazilian young males. the validity of vo2max to predict the ace genotype was also analyzed. methods: a homogeneous group of moderately active young males were evaluated in a 1,600 m running track test (v1600m; m.min-1) and in an incremental treadmill test for vo2max determination. subsequently, the actual and the predicted [(0.177*v1600m) + 8.101] vo2max were compared to ace genotypes. results: the vo2max and v1600m recorded for dd, id and ii genotypes were 45.6 (1.8); 51.9 (0.8) and 54.4 (1.0) ml.kg-1.min-1 and 211.2 (8.3); 249.1 (4.3) and 258.6 (5.4) m.min-1 respectively, and were significantly lower for dd carriers (p< 0.05). the actual and predicted vo2max did not differ from each other despite ace genotype, but the agreement between actual and estimated vo2max methods was lower for the dd genotype. conclusion: it was concluded that there is a possible association between ace genotype, cardiovascular fitness and middle-distance running performance of moderately active young males and that the accuracy of vo2max prediction may also depend on the ace genotype of the participants.
%K angiotensin-converting enzyme
%K i [d polymorphism]
%K vo2max
%K middle-distance running.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0066-782X2012000400005&lng=en&nrm=iso&tlng=en