%0 Journal Article %T Morbilidad y mortalidad por cardiopat¨ªa isqu¨¦mica en el Instituto Mexicano del Seguro Social. Estudio ecol¨®gico de tendencias en poblaci¨®n amparada por el Instituto Mexicano del Seguro Social entre 1990 y 2008 %A Escobedo-de la Pe£¿a %A Jorge %A Rodr¨ªguez-¨¢brego %A Gabriela %A Buitr¨®n-Granados %A Luisa Virginia %J Archivos de cardiolog¨ªa de M¨¦xico %D 2010 %I Scientific Electronic Library Online %X objective: to analyze secular trends of coronary heart disease morbidity and mortality in mexicans protected by the mexican institute of social security. methods: an ecological trend analysis study was conducted on coronary heart disease morbidity and mortality in the mexican population protected by the institute. all deaths were adjusted for miscoding and misclassification and rates were age-adjusted according to the age distribution proposed by the world health organization. hospital discharges, as well as the number of patients seeking medical care for coronary heart disease, were analyzed as an indirect incidence measure. fatality rates and the mean number of hospitalization days were also estimated. results: coronary heart disease mortality has shown a stable trend at the end of last century and a descending trend in the first years of this century, both in males (r= -0.84; r2=0.70; p <0.001) as in females (r = -0.76; r2 =0.57; p <0.001). there is an age-effect on mortality; mortality is higher in males, mainly at younger ages (male-female rate = 3.44). fatality rates have progressively decreased and the mean age of death has increased by four years in the last two decades. conclusions: the stable trend and later descent on coronary heart disease mortality may be best explained by an increase in the quality of health care and secondary prevention. nevertheless, there is a need to strengthen primary prevention by modifying exposure to major cardiovascular risk factors in mexicans. %K coronary heart disease %K myocardial infarction %K mortality %K ecologic study %K mexico. %U http://www.scielo.org.mx/scielo.php?script=sci_abstract&pid=S1405-99402010000400008&lng=en&nrm=iso&tlng=en