%0 Journal Article
%T Miocarditis aguda primaria. Experiencia de diez a£¿os en el Instituto Nacional de Cardiolog¨ªa "Ignacio Ch¨¢vez"
%A Guillen-Ortega
%A Fernando
%A Soto
%A Mar¨ªa Elena
%A Reyes
%A Pedro A
%J Archivos de cardiolog¨ªa de M¨¦xico
%D 2005
%I Scientific Electronic Library Online
%X acute myocarditis (am) is associated with viral infections: coxsackie and echoviruses among others. autoimmunity has been proposed as a pathogenic mechanism. benefit of classic immunosuppression (prednisone-azathioprine) or immunomodulation (monomeric-human igg) is still uncertain. objective: to review incidence and clinical approach to am at a cardiology referral center. material and methods: a 10-yeard period (1992-2003) is reviewed. a standard ques-tionary was applied to 49 consecutive patients referred by clinicians with a diagnosis of am. results: am was found in 17 women and 32 men, median age 24 and 28 years, respectively. they presented heart failure with dyspnea/ortop-nea (70-47%), peripheral edema/jugular vein plethora (41-37%), chest pain, and tachycardia (50%), nyha functional class was iii-iv in 22. the ekg showed sinus tachycardia or conduction defects. transthoracic echocardiograms in 47 cases showed ef (mean) of 41% with enlarged left ventricle diameter. antivirus antibodies were present in 54% of those cases studied, coxsackie or echovirus were identified through a serologic assay. twenty-nine (61%) of our cases developed dilated cardiomyopathy, three patients died. it is not possible to reach a conclusion regard to immunomodulation therapy, because it was applied to only 12 patients. conclusions: at the instituto nacional de cardiolog¨ªa "i. ch¨¢vez", am depicts an incidence of 1/1,000 patients a year. it is necessary to standardize the clinical approach for diagnosis and treatment, progression to dilated cardiomyopathy and deadth during acute stage occurs in two-thirds of our patients
%K myocarditis
%K cardiomyopathy
%K enterovirus.
%U http://www.scielo.org.mx/scielo.php?script=sci_abstract&pid=S1405-99402005000700010&lng=en&nrm=iso&tlng=en