%0 Journal Article
%T Impacto de la maniobra de inspiraci¨®n profunda en el intercambio gaseoso del sujeto con obesidad severa e hipertensi¨®n arterial pulmonar asociada a s¨ªndrome de Eisenmenger
%A Santos-Mart¨ªnez
%A Luis-Efren
%A Mart¨ªnez-Guerra
%A Mar¨ªa-Luisa
%A Bautista
%A Edgar
%A Castillo
%A Francisco
%A Casta£¿¨®n
%A Alicia
%A Pulido
%A Tom¨¢s
%A Hern¨¢ndez
%A Jos¨¦-Luis
%A Sandoval
%A Julio
%J Archivos de cardiolog¨ªa de M¨¦xico
%D 2008
%I Scientific Electronic Library Online
%X obesity and eisenmenger's syndrome are entities widely studied. however, its association is unusual and has not been reported. a wide range of gas exchange abnormalities have been describe in both groups. in the severe obese patients this abnormalities are attributed to a ventilation/perfusion mismatch and to an increase pulmonary venous-arterial shunt, that correlates with the lung volume. in severe obese patients with the eisenmenger's syndrome, this correlation is unknown. methods: we studied 28 obese subjects paired by body mass index > 30 kg/m2. assigned to two groups, obese with eisenmenger's syndrome and obese without the syndrome. clinical variables, respiratory function, echocardiography and gas exchange pre and post-deep breathing maneuver were obtained. statistical analysis: the variables are expressed with mean¡Àstandard deviation. student t test for paired groups and pearson correlation coefficient were gathered for the differences and associations between groups. a p-value <0.05 was considered significant. result: age was 48.57 ¡À 10.32 vs 60.86 ¡À 10.47 y.o. respectively, p < 0.004. systolic pulmonary arterial pressure 104.36 ¡À 37 vs 50.1 ¡À 12 mm hg, p < 0.001. the arterial oxygen pressure at rest and during the deep breathing maneuver in each group was: 51.64 ¡À 6.38 vs 57.14 ¡À 11, p < 0.188 and 56.29 ¡À 11.15 vs 72 ¡À 11.83, p < 0.001; venous-arterial shunt 12.79 ¡À 3.66 vs 13.07 ¡À4.84, p< 0.767 and 9.21 ¡À3.77 vs 6.5 ¡À 2.28, p < 0.001; alveolar arterial oxygen difference 271.14 ¡À 79.92 vs 243.79 ¡À 92.07, p < 0.001, respectively. conclusion: obese subjects with eisenmenger's syndrome, did not have significant improvement of gas exchange with the deep breathing maneuver.
%K gas exchange
%K deep breathing
%K congenital heart disease.
%U http://www.scielo.org.mx/scielo.php?script=sci_abstract&pid=S1405-99402008000300004&lng=en&nrm=iso&tlng=en