%0 Journal Article %T Impacto de un programa de prevenci¨®n de infecciones respiratorias en lactantes prematuros de alto riesgo: estudio prospectivo y multic¨¦ntrico %A Bauer %A Gabriela %A Bossi %A Lucrecia %A Santoalla %A Marisa %A Rodr¨ªguez %A Susana %A Fari£¿a %A Diana %A Speranza %A Ana M. %J Archivos argentinos de pediatr£¿-a %D 2009 %I Sociedad Argentina de Pediatria %X respiratory tract infections (rti), specially those caused by respiratory syncytial virus (rsv) are of central concern in high-risk preterm infant care. prevention programs including new and costly interventions should be evaluated in terms of efectivity and impact. objectives. to evaluate feasibility and results of a national health ministry pilot program for severe rti prevention in high-risk infants. methods. seven high-risk follow-up clinics from the public healthcare system were selected for a prospective, multicentric study. between may and september 2007, a pilot program comprising healthcare team training, parental education, rsv pasive immunoprophylaxis, rti patient care end results evaluation was implemented. indicators were used to evaluate feasibility; efectivity was estimated comparing study results with two historical controls. results. 183 infants were incorporated, 5 were lost and 1 died from cardiac disease. a rti management guideline was elaborated among participating centers; parents assisted to educational workshops; palivizumab was given to participating infants up to three doses. rti hospital admission rate for the study group was 20% (7% rsv-related), compared to 42% (26% rsv-related) and 37% (29% rsv-related) in control groups (p< 0.0001 and p= 0.02, respectively). conclusions. program implementation was feasible and readily accepted by healthcare teams. rti hospital admissions rates, in general and rsv-related, were significatively lower than local previous studies. %K premature infants %K respiratory tract infections %K prevention and control %K effectiveness program. %U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0325-00752009000200003&lng=en&nrm=iso&tlng=en