%0 Journal Article
%T Cardiolog¨ªa "basada en la evidencia": aplicaciones pr¨¢cticas de la epidemiolog¨ªa. I. La valoraci¨®n de medicamentos o terapias novedosas
%A Trejo-Guti¨¦rrez
%A Jorge F
%A L¨®pez-Jim¨¦nez
%A Francisco
%J Archivos de cardiolog¨ªa de M¨¦xico
%D 2011
%I Scientific Electronic Library Online
%X the substantial increase of randomized controlled trials demand familiarity with the essential aspects of their design and performance by the cardiologist, particularly the adequate interpretation and applicability of the results. in this clinically-based review, we discuss some important aspects in the assessment of novel contemporary therapy such as the use and analysis of composite endpoints; implications from early termination of trials and extrapolation of results to the population.
%K randomized controlled trial
%K critical analysis
%K novel therapy
%K usa.
%U http://www.scielo.org.mx/scielo.php?script=sci_abstract&pid=S1405-99402011000100010&lng=en&nrm=iso&tlng=en