%0 Journal Article
%T Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil
%A Peirano
%A Gisele
%A Souza
%A Fl¨˘via dos Santos
%A Rodrigues
%A Dalia dos Prazeres
%J Mem¨®rias do Instituto Oswaldo Cruz
%D 2006
%I Instituto Oswaldo Cruz, Minist¨¦rio da Sa¨˛de
%R 10.1590/S0074-02762006000300003
%X a total of 296 shigella spp. were received from state public health laboratories, during the period from 1999 to 2004, by national reference laboratory for cholera and enteric diseases (nrlced) - ioc/fiocruz, rio de janeiro, brazil. the frequency of shigella spp. was: s. flexneri (52.7%), s. sonnei (44.2%), s. boydii (2.3%), and s. dysenteriae (0.6%). the most frequent s. flexneri serovars were 2a and 1b. the highest incidence rates of shigella isolation were observed in the southeast (39%) and northeast (34%) regions and the lowest rate in the south (3%) of brazil. strains were further analyzed for antimicrobial susceptibility by disk diffusion method as part of a surveillance program on antimicrobial resistance. the highest rates of antimicrobial resistance were to trimethoprim-sulfamethozaxole (90%), tetracycline (88%), ampicillin (56%), and chloramphenicol (35%). the patterns of antimicrobial resistance among shigella isolates pose a major difficulty in the determination of an appropriate drug for shigellosis treatment. continuous monitoring of antimicrobial susceptibilities of shigella spp. through a surveillance system is thus essential for effective therapy and control measures against shigellosis.
%K shigella
%K serovars
%K antimicrobial resistance surveillance
%K brazil.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762006000300003&lng=en&nrm=iso&tlng=en