%0 Journal Article %T Outbreak of carbapenem-resistant Klebsiella pneumoniae: two-year epidemiologic follow-up in a tertiary hospital %A Pereira %A Graziella Hanna %A Garcia %A Doroti O %A Mostardeiro %A Marcelo %A Fanti %A Karina SVN %A Levin %A Anna S %J Mem¨®rias do Instituto Oswaldo Cruz %D 2013 %I Instituto Oswaldo Cruz, Minist¨¦rio da Sa¨²de %R 10.1590/S0074-02762013000100019 %X this study describes a carbapenem-resistant klebsiella pneumoniae (crkp) outbreak that occurred from october 2008-december 2010. polymerase chain reaction assays were performed to detect the blakpc gene and molecular typing was performed using pulsed-field gel electrophoresis (pfge). there were 33 crkp infections; pfge revealed five genotypes: genotype a in five (15%), b in 18 (55%), c in eight (24%) and two unique profiles. genotype b was disseminated in all hospital units and belonged to the same clone identified in 11 different hospitals in the state of s£¿o paulo. sixteen (48%) patients died. seven isolates (21%) were resistant to polymyxin b and 45% were resistant to tigecycline and amikacin. %K carbapenem-resistant k. pneumoniae %K nosocomial outbreak %K polymyxin resistance. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762013000100019&lng=en&nrm=iso&tlng=en