%0 Journal Article
%T Agranulocitosis secundaria al uso de vasoprotectores
%A Membrado G¨®mez
%A S.
%A V¨¢zquez Perfecto
%A G.
%A ¨¢lvarez Esteban
%A Ma. M.
%J Medifam
%D 2003
%I Scientific Electronic Library Online
%R 10.4321/S1131-57682003000100008
%X the presence of agranulocytosis is signalled by a concentration of neutrophils lower than 500 per mm3. we present the case of an 88 years old man who suffered an agranulocytosis after a treatment with calcium dobesilate and troxerutin prescribed to him after a diagnosis of diabetic retinopathy. although there are only a few cases of calcium dobesilate related agranulocytosis and none related to troxerutin, the efficacy of these phlebotonics has not been demonstrated. given that agranulocytosis has a mortality rate of approximately 15%, risks and benefits should be balanced before the prescription of these drugs.
%K calcium dobesilate
%K troxerutin
%K agranulocytosis.
%U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S1131-57682003000100008&lng=en&nrm=iso&tlng=en