%0 Journal Article
%T Comparative evaluation under routine conditions of the nitrate reduction assay, the proportion assay and the MGIT 960 assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis
%A Fonseca
%A Leila de Souza
%A Vieira
%A Gisele Betzler de Oliveira
%A Sobral
%A Luciana Fonseca
%A Ribeiro
%A Elizabete Oliveira
%A Marsico
%A Anna Grazia
%J Mem¨®rias do Instituto Oswaldo Cruz
%D 2012
%I Instituto Oswaldo Cruz, Minist¨¦rio da Sa¨²de
%R 10.1590/S0074-02762012000100021
%X the performance of the nitrate reductase assay (nra) was compared with the proportion method (pm) on lowenstein-jensen medium and the bactec mgit960 assay under routine conditions using 160 clinical isolates of mycobacterium tuberculosis with a high proportion of resistant strains. the mean time to obtain results was 8.8 days and the overall agreements between nra and pm and nra and m960 were 95% and 94%, respectively. nra was easy to perform and represents a useful tool for the rapid screening of drug-resistant m. tuberculosis strains in low-resource countries.
%K tuberculosis
%K nitrate reductase assay
%K drug susceptibility.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762012000100021&lng=en&nrm=iso&tlng=en