%0 Journal Article %T High resolution image in bone biology I: Review of the literature %A Cano %A Jorge %A Campo %A Juli¨¢n %A Vaquero %A Juan Jos¨¦ %A Mart¨ªnez %A Jose Mar¨ªa %A Bascones %A Antonio %J Medicina Oral, Patolog¨ªa Oral y Cirug¨ªa Bucal (Internet) %D 2007 %I Scientific Electronic Library Online %X bone microstructure has usually been assessed by obtaining samples invasively and analyzing them with conventional histomorphometric methods. improvements in high-resolution image acquisition systems have enabled non-invasive assessment of bone morphology and a more precise 3-d evaluation by means of "virtual biopsies", permitting bone assessment in regeneration or remodeling processes. this review describes the characteristics and limitations of bone assessment using different high-resolution image systems (synchrotron-radiation computed tomography, micro-computed tomography, acoustic scanning microscope; micro-magnetic resonance imaging). morphometric variables that can be obtained from these images are reported and compared with conventional histomorphometric variables. %K high-resolution image %K bone biology %K virtual biopsy. %U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S1698-69462007000600009&lng=en&nrm=iso&tlng=en