%0 Journal Article %T Uso de oxigenador de membrana extracorp¨®reo en pacientes con insuficiencia respiratoria aguda grave refractaria en la epidemia de gripe estacional 2010-2011 por influenza A (H1N1) en Espa£¿a %A Bonastre %A J. %A Suberviola %A B. %A Pozo %A J.C. %A Guerrero %A J.E. %A Torres %A A. %A Rodr¨ªguez %A A. %A Mart¨ªn-Loeches %A I. %A %J Medicina Intensiva %D 2012 %I Ediciones Doyma, S.L. %X objective: to describe the use of extracorporeal membrane oxygenation (ecmo) in refractory respiratory failure. design: a prospective, observational, multi-center study was carried out. setting: intensive care units (icu) in 148 spanish hospitals. patients: subjects admitted during epidemic weeks 50-52 of 2010 and weeks 1-4 of 2011, receiving respiratory support with ecmo. main variables of interest: clinical and blood gas features, complications and survival of patients with ecmo. results: out of 300 icu admitted patients, 239 (79.6%) were mechanically ventilated. ecmo was available in only 5 icus. nine patients were treated with ecmo (3% of the total and 3.2% of the ventilated patients). in 77.7% of the cases some hypoxemia rescue technique was previously used. ecmo was initiated when ards proved refractory to standard treatment. ecmo therapy was started a median of 4.5 days after the onset of mechanical ventilation. the median duration of ecmo was 6 days. veno-venous (vv) ecmo was the most frequent cannulation mode (88.9%). four patients had complications associated with ecmo therapy. the median icu and hospital stay was 17 and 29 days, respectively. in five patients (55.5%), ecmo assistance was satisfactory suspended. the icu and hospital survival rate was 44.4%. conclusions: the use of ecmo in refractory respiratory failure in patients with influenza a (h1n1) is rare in spain. the hospital survival achieved with its use allows it to be regarded as a possible rescue technique in these patients. %K extracorporeal membrane oxygenation (ecmo) %K influenza a (h1n1) %K critically ill patients. %U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0210-56912012000300005&lng=en&nrm=iso&tlng=en