%0 Journal Article %T Histiocitosis de c¨¦lulas de langerhans en hueso parietal %A Quir¨®s Alp¨ªzar %A Jos¨¦ Luis %A Barrantes Monge %A Ricardo %J Medicina Legal de Costa Rica %D 2012 %I Asociaci¨®n Costarricense de Medicina Forense %X the langerhans cell histiocytosis is a group of diseases with a single or multisystem involvement, it¡äs clinic and complications vary depending on the tissue affected and the extent of the injury. the case of a 2 £¿ years old female patient was presented, with a mass on the skull in the left parietal area of 22 days, 6-7 cm long, painful, deforms facial image and loss of appetite. the ct scan showed a fracture of the parietal bone, increase of homogeneous solid volume without calcification. the treatment was a tumor resection, craniotomy and cranioplasty, the histopathological study showed immunohistochemically cells s100, cd1a and cd68 positive %K histiocytosis %K eosinophilic granuloma %K histiocytosis x %K langerhans cell histiocytosis %K langerhans cells %K lytic lesions %K biopsy %K immunohistochemistry %K cd1a %K s100 %K cd 68. %U http://www.scielo.sa.cr/scielo.php?script=sci_abstract&pid=S1409-00152012000100012&lng=en&nrm=iso&tlng=en