%0 Journal Article
%T Seroprevalencia de HTLV-1/2 en donantes de sangre de la Provincia de Misiones
%A Malan
%A Richard
%A Berini
%A Carolina A.
%A Eirin
%A Mar¨ªa E.
%A Delfino
%A Cecilia M.
%A Pedrozo
%A Williams
%A Krupp
%A Ram¨®n
%A Garc¨ªa Plichta
%A Atilio
%A Biglione
%A Mirna M.
%J Medicina (Buenos Aires)
%D 2010
%I Fundaci¨®n Revista Medicina
%X human t-cell lymphotropic viruses type 1 (htlv-1), the first human oncoretrovirus to be discovered, is the etiologic agent of adult t-cell leukemia (atl) and htlv-1 associated mielopathy or tropical spastic paraparesis (ham/tsp). it is endemic worldwide, including the north of argentina where both associated diseases have also been detected. no etiologic role has been described for htlv-2, although it has been associated with ham/tsp-like neurologic syndromes. both retroviruses are endemic in native populations of the americas, africa and at-risk populations. they are transmitted through sex contact, parenterally and from mother to child. the aim of this study was to estimate the seroprevalence of htlv-1/2 in a blood donor population from misiones province. a total of 6912 accepted blood donations in 2008 were analyzed. htlv-1/2 screening was performed with elisa and particle agglutination, and reactive samples were confirmed by western blot. from the total, 5 samples resulted seropositive with a final prevalence of 0.00072. out of the 5 positive samples, one was an htlv, three htlv-1 and one htlv-2. these blood donors were residents of posadas, eldorado and ober¨¢, with no risk antecedents. this study demonstrates the presence of htlv-1/2 in a population of misiones with a prevalence rate similar to those reported among blood donors from non-endemic areas.
%K blood donors
%K misiones
%K htlv-1/2.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0025-76802010000100013&lng=en&nrm=iso&tlng=en