%0 Journal Article
%T Estudio epidemiol¨®gico, cl¨ªnico e inmunol¨®gico de pacientes infectados con HIV y HTLV-1
%A Scapellato
%A Pablo G.
%A Bottaro
%A Edgardo G.
%A Seoane
%A Mar¨ªa B.
%A Rodriguez Brieschke
%A Mar¨ªa T.
%A Scapellato
%A Jos¨¦ L.
%A Dato
%A Adriana
%A Vidal
%A Gabriela I.
%J Medicina (Buenos Aires)
%D 2004
%I Fundaci¨®n Revista Medicina
%X we studied the prevalence of antibodies against htlv-1 among every hiv-infected outpatients assisted in our hospital between january 1st 2000 and june 30th 2003. we reviewed the epidemiological data, clinical findings, viral load and cd4 cells-count, comparing coinfected with non htlv-1 coinfected. we found a prevalence of htlv-1 infection of 8.1% (23/282); 8.5% (12/141) in men and 7.8% (11/141) in women [or=0.91(0.36<or<2.3) p=0.8]; 12.4% (16/129) among patients users of illicit drugs and 4.6% (7/152) among non-users [or=2.93 (1.09<or<8.17) p=0.03]; 20.8% (16/77) in injecting drugs users (idu) and 3.4% (7/205) in non-idu patients [p=0.000006 or=7.42 (2.71<or<20.9)]. ninety six patients (96/282) had history of aids defining diseases (add). no diferences in the add were found among coinfected and no coinfected patients. no patient developed any disease relative to htlv-1. the mean of cd4-cells among htlv-1 coinfected with history of add n£¿ive patients (n=7) was 211 cells/ml, and 87.9 cells/ml among those not-coinfected (n=55) [t-test=2.82; p=0.006]. the viral load was similar among every investigated group of patients. we found a high prevalence of htlv-1 infection in hiv-infected patients (higher among idu). the cd4-cell count of patients suffering from an aids defining disease was higher among htlv-1/hiv coinfected patients than in singly hiv infected, this could show a grade of missfunction of cd4-cells in coinfected patients.
%K hiv
%K htlv-1
%K prevalence
%K aids
%K cd4
%K substance abuse
%K intravenous drug users.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0025-76802004000500006&lng=en&nrm=iso&tlng=en