%0 Journal Article
%T Caracter¨ªsticas generales de 29 pacientes con vasculitis de peque£¿os vasos
%A Di Benedetto
%A Nicol¨¢s
%A L¨®pez Mujica
%A Mar¨ªa Ximena
%A Fern¨¢ndez
%A Mart¨ªn E.
%A Tour¨®n
%A Mar¨ªa
%A Mu£¿oz
%A Sebastian A.
%A Allievi
%A Alberto
%J Medicina (Buenos Aires)
%D 2010
%I Fundaci¨®n Revista Medicina
%X the objective of this series was to describe the general characteristics and clinical manifestations of patients with small vessel vasculitis who were assisted in the autoimmunity department of a community public hospital and to compare the results with the literature. clinical records under the label of vasculitis in a period of 16 years were reviewed in a retrospective way. all patients selected fulfilled diagnostic criteria of small vessel vasculitis. the data were extracted and the analysis of survival was completed by phone. later a bibliographical search was carried out and the results were compared. thirteen patients with wegener's granulomatosis, 6 with churg-strauss syndrome and 10 with microscopic polyangiitis were included. fifty five percent (16) were under 55 years old when diagnosis was made and male/female ratio was 2.6 to 1. the diagnostic delay was over a year in 46% of the cases. respiratory and ear-nose-throat were the most frequently affected systems. anti-neutrophil cytoplasmic antibodies were present in 79% of patients. overall mortality was 24% (7/29). there were several differences between the results of our series and the literature: the presentation form, affected systems and percentage of patients with anti-neutrophil cytoplasmic antibodies. greater diagnostic delay and worse prognosis were observed in anti-neutrophil cytoplasmic antibody negative patients. special attention should be given to these antibodies since they constitute a significant tool at the time of diagnosis.
%K vasculitis
%K wegener granulomatosis
%K churg-strauss syndrome.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0025-76802010000200003&lng=en&nrm=iso&tlng=en