%0 Journal Article
%T In vitro bioactivity and cytotoxicity of chemically treated glass fibers
%A Andrade
%A £¿ngela Le£¿o
%A Turchetti-Maia
%A Regina Maria de Marco
%A Lopes
%A M¨ªriam Teresa Paz
%A Salas
%A Carlos Edmundo
%A Domingues
%A Rosana Zacarias
%J Materials Research
%D 2004
%I ABM, ABC, ABPol, SBCC, SBCr, SBMM, SBPMat
%R 10.1590/S1516-14392004000400019
%X samples of a commercial glass fiber fm£¿ (fiber max) were used to test the efficacy of a chemical sol-gel surface treatment to enhance their bioactivity. after treatment with tetraethoxysilane (teos), individual fiber samples were soaked into a simulated body fluid (sbf) solution, from which they were removed at intervals of 5 and 10 days. micrographs obtained by scanning electron microscopy (sem) analysis of samples chemically treated with teos revealed the formation of a hydroxyapatite (ha) coating layer after 5 days into sbf solution. fourier transform infrared spectroscopic (ftir) analyses confirmed that the coating layer has p-o vibration bands characteristic of ha. the in vitro cytotoxicity was evaluated using a direct contact test, minimum essential medium elution test (iso 10993-5) and mtt assay. fibers immersed in sbf and their extracts exhibited lower cytotoxicity than the controls not subjected to immersion, suggesting that sbf treatment improves the biocompatibility of the fiber.
%K glass fiber
%K chemical treatment
%K bioactivity
%K cytotoxicity.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-14392004000400019&lng=en&nrm=iso&tlng=en