%0 Journal Article
%T Lupus eritematoso neonatal: reporte de cuatro casos
%A Perez
%A Maria Fernanda
%A Torres
%A Maria Eugenia de
%A Buj¨¢n
%A Mar¨ªa Marta
%A Lano£¿l
%A Agustina
%A Cervini
%A Andrea Bettina
%A Pierini
%A Adri¨¢n Mart¨ªn
%J Anais Brasileiros de Dermatologia
%D 2011
%I Sociedade Brasileira de Dermatologia
%R 10.1590/S0365-05962011000200021
%X neonatal lupus erythematosus is a very rare disease, clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart block. generally, when patients have skin manifestations, they have no cardiac defects and vice-versa; however, in 10% of cases these manifestations may coexist. other findings may include hematologic, hepatic and neurological abnormalities. this condition is caused by the transplacental passage of maternal autoantibodies against ro (95%), la and, less frequently, u1-ribonucleoprotein (u1-rnp). the present case report describes four patients with clinical, histopathological and immunological findings compatible with neonatal lupus erythematosus, their treatment and progress.
%K cutaneous
%K heart diseases
%K lupus erythematosus
%K pediatrics.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0365-05962011000200021&lng=en&nrm=iso&tlng=en