%0 Journal Article
%T Remiss£¿o de ret¨ªculo-histiocitose multic¨ºntrica com terapia combinada com infliximabe
%A Rstom
%A S¨ªlvia Arroyo
%A Menezes
%A Bruna Fernandes Padilha de
%A Maitto
%A Juliana Britta
%A Cabrera
%A Rafael Alberto Aragon
%A Machado Filho
%A Carlos D£¿App Santos
%J Anais Brasileiros de Dermatologia
%D 2008
%I Sociedade Brasileira de Dermatologia
%R 10.1590/S0365-05962008000600007
%X multicentric reticulohistiocytosis is an extremely rare systemic disorder of unknown etiology. it is characterized by a severe symmetric polyarthritis which can progresses to a mutilant arthritis and papulonodular skin and mucosal lesions. the diagnostic of multicentric reticulo histiocytosis is histopathologic. approximately one-third of the adults patients have association with malignancies. there is no uniform treatment regimen for multicentric reticulohistiocytosis. we present a case of a 46-year woman with a classical clinical picture of multicentric reticulohistiocytosis. the patient received treatment with biological immunemodulators with marked results.
%K histiocytosis
%K immunologic factors
%K reticulum.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0365-05962008000600007&lng=en&nrm=iso&tlng=en