%0 Journal Article
%T Chiral Allylsilane Additions to Chiral alpha-Substituted Aldehydes
%A Dias
%A Luiz C.
%A Giacomini
%A Rosana
%J Journal of the Brazilian Chemical Society
%D 1998
%I Sociedade Brasileira de Qu¨ªmica, SBQ
%R 10.1590/S0103-50531998000400008
%X chiral allylsilane 3 reacted with chiral a-methyl-b-siloxy-aldehydes to afford the corresponding 1,4-syn-products with good diastereoselectivities independent of the absolute stereochemistry of these aldehydes. the best selectivities are observed when the reactions are carried out by transmetallation of the allylsilane 3 using tin (iv) chloride in ch2cl2, at -78 ¡ãc, before addition of the aldehydes.
%K chiral allylsilane
%K transmetallation
%K 1
%K 4-asymmetric induction
%K polyacetate derived natural products.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50531998000400008&lng=en&nrm=iso&tlng=en