%0 Journal Article
%T Chemical composition and antifungal activity of the essential oil of Hyptis ovalifolia Benth. (Lamiaceae)
%A Oliveira
%A Cec¨ªlia M. A. de
%A Silva
%A Maria do Ros¨¢rio R.
%A Kato
%A Luc¨ªlia
%A Silva
%A Cleuza C. da
%A Ferreira
%A Heleno D.
%A Souza
%A L¨²cia K. H.
%J Journal of the Brazilian Chemical Society
%D 2004
%I Sociedade Brasileira de Qu¨ªmica, SBQ
%R 10.1590/S0103-50532004000500023
%X the leaves of hyptis ovalifolia benth. (lamiaceae) were subjected to hydrodistillation and the resulting volatiles were investigated by gc/ms. the main constituent representing 60% of the essential oil was isolated by column chromatography and identified by spectroscopic methods as (r)-6-[(z)-1-heptenyl]-5,6-dihydro-2h-pyran-2-one (1). this compound showed strong in vitro activity against four dermatophyte fungi microsporum canis, microsporum gypseum, tricophyton mentagrophytes, and tricophyton rubrum (a total of 60 strains) with a minimal inhibitory concentration observed in the range of 125-7.8 mg ¦Ìl-1.
%K hyptis ovalifolia
%K essential oil
%K antifungal activity
%K lamiaceae
%K (r)-6-[(z)-1-heptenyl]-5
%K 6-dihydro-2h-pyran-2-one.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532004000500023&lng=en&nrm=iso&tlng=en