%0 Journal Article %T Dipeptide metabolites from the marine derived bacterium Streptomyces acrymicini %A Hern¨˘ndez %A Isara L. C. %A Macedo %A Mario L. %A Berlinck %A Roberto G. S. %A Ferreira %A Antonio G. %A Godinho %A Mirna J. L. %J Journal of the Brazilian Chemical Society %D 2004 %I Sociedade Brasileira de Qu¨Şmica, SBQ %R 10.1590/S0103-50532004000300017 %X the chemical investigation of the crude extract obtained from the growth media of the marine-derived actinomycete streptomyces acrimycini isolated from marine sediments led to the isolation of two new dipeptide derivatives: 8-amino-[ 1,4] diazonane-2,5-dione (1) and leucyl-4-hydroxyproline (3). the dipeptides were isolated from the growth media by a series of chromatographic steps, and identified by analysis of spectroscopic data. the macrocyclic carbon backbone of 8-amino-[ 1,4] diazonane-2,5-dione has been previously reported only once in marinobactins, siderophores isolated from the marine bacterium marinobacter sp. %K 8-amino-[ 1 %K 4] diazonane-2 %K 5-dione %K leucyl-4-hydroxyproline %K streptomyces acrimycini. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532004000300017&lng=en&nrm=iso&tlng=en