%0 Journal Article
%T Triiodoisocyanuric acid: a new and convenient reagent for regioselective iodination of activated arenes
%A Ribeiro
%A Rodrigo da S.
%A Esteves
%A Pierre M.
%A Mattos
%A Marcio C. S. de
%J Journal of the Brazilian Chemical Society
%D 2008
%I Sociedade Brasileira de Qu¨Şmica, SBQ
%R 10.1590/S0103-50532008000700002
%X triiodoisocyanuric acid (tica) was prepared in 90% yield by heating trichloroisocyanuric acid with iodine in a sealed tube. the reaction of tica with activated arenes in acetonitrile led to an efficient and highly regioselective formation of the corresponding iodoarenes, in 73-93% isolated yield. aniline and phenol are monoiodinated regioselectively using meoh (53%) and ch2cl2 (88%) as solvents, respectively.
%K triiodoisocianuric acid
%K iodination
%K activated aromatic compound
%K iodoarene
%K electrophilic halogenation.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532008000700002&lng=en&nrm=iso&tlng=en