%0 Journal Article
%T Preparation of novel trifluoroacetylketene O,N-acetals and trifluoromethyl-containing S,S-sulfoximido N-substituted heterocycles
%A Bonacorso
%A Helio G.
%A Vezzosi
%A Renata P.
%A Rodrigues
%A Isadora R.
%A Drekener
%A Roberta L.
%A Porte
%A Liliane M. F.
%A Flores
%A Alex F. C.
%A Zanatta
%A Nilo
%A Martins
%A Marcos A. P.
%J Journal of the Brazilian Chemical Society
%D 2009
%I Sociedade Brasileira de Qu¨Şmica, SBQ
%R 10.1590/S0103-50532009000700024
%X two new trifluoroacetylketene o,n-acetals [cf3c(o)ch=c(oet)(ns(o)r2), where r = ch3, ph] derived from the reaction of 4,4-diethoxy-1,1,1-trifluorobut-3-en-2-one [cf3c(o)ch=c(oet)2] with s,s-dimethyl- and s-methyl-s-phenyl-sulfoximide [hn=s(o)r2], in the presence of triethylamine, have been obtained, in 60-72% yields, and applied in the synthesis of s,s-dimethylsulfoximido-substituted pyrazoles, isoxazoles and pyrimidines, in 55-89% yields, from the reactions of 4-ethoxy-4-(s,s-dimethylsulfoximido)-1,1,1-trifluorobut-3-en-2-one with hydrazines, hydroxylamine hydrochloride and acetylguanidine.
%K acetals
%K sulfoximides
%K pyrazoles
%K isoxazoles
%K pyrimidines.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532009000700024&lng=en&nrm=iso&tlng=en