%0 Journal Article
%T Anti-inflammatory activity of the apolar extract from the seaweed Galaxaura marginata (Rhodophyta, Nemaliales)
%A Rozas
%A E.
%A Freitas
%A J. C.
%J Journal of Venomous Animals and Toxins including Tropical Diseases
%D 2007
%I Centro de Estudos de Venenos e Animais Pe?onhentos - CEVAP, Universidade Estadual Paulista - UNESP
%R 10.1590/S1678-91992007000200011
%X the red seaweed galaxaura marginata (ellis & solander) lamouroux, well known by the antibacterial activity of its polar extract and the cytotoxic activity of its oxygenated desmosterol, showed anti-inflammatory action in its apolar fraction. topical anti-inflammatory activity was observed in samples collected at sŁżo sebastiŁżo channel, northern littoral of sŁżo paulo state, brazil. the apolar extract and its fractions obtained through thin-layer chromatography (tlc) reduced the topical inflammation produced by croton oil in mouse ear. such data indicated that the apolar extract from the marine red alga g. marginata displayed anti-inflammatory activity (since 1mg/ear extract reduced 95ˇŔ0.5% inflammation), which could be the result of the synergic activity of the four fractions present in the apolar extract.
%K seaweed
%K galaxaura marginata
%K inflammation
%K croton oil
%K edema
%K anti-inflammatory agents.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1678-91992007000200011&lng=en&nrm=iso&tlng=en