%0 Journal Article
%T Pre-surgical mood disorders associated to worse post-surgical seizure outcome in patients with refractory temporal lobe epilepsy and mesial temporal sclerosis
%A Ara¨²jo Filho
%A Gerardo Maria de
%A Gomes
%A Francinaldo Lobato
%A Mazetto
%A Lenon
%A Marinho
%A Murilo Martinez
%A Tavares
%A Igor Melo
%A Caboclo
%A Lu¨ªs Ot¨¢vio Sales Ferreira
%A Yacubian
%A Elza M¨¢rcia Targas
%A Centeno
%A Ricardo Silva
%J Journal of Epilepsy and Clinical Neurophysiology
%D 2012
%I Liga Brasileira de Epilepsia
%R 10.1590/S1676-26492012000100006
%X objectives: this study aims at verifying the impact of pre-surgical pd on seizure outcome in patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (tle-mts). methods: after previous consent, retrospective data from 115 surgically treated (corticoamygdalohyppocampectomy) tle-mts patients (65 females; 56.5%) were analyzed. psychiatric evaluations were performed through dsm-iv criteria. engel ia was established as a favorable prognosis. results: forty-five patients (41.6%) were classified as engel ia, while 47 (40.8%) presented pre-surgical pd. depression (or=5.11; p=0.004) appeared as a risk factor associated to a non-favorable seizure outcome. conclusion: in patients with refractory tle-mts, the presence of depression predicts an unfavorable outcome.
%K temporal lobe epilepsy
%K mesial temporal sclerosis
%K epilepsy surgery
%K psychiatric disorders
%K seizure outcome.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1676-26492012000100006&lng=en&nrm=iso&tlng=en