%0 Journal Article %T ESTUDIO DEL POLIMORFISMO HINFI DEL GEN PIT-1 Y SU ASOCIACI¨®N CON CARACTER¨ªSTICAS DE TIPO, PRODUCCI¨®N DE LECHE Y D¨ªAS ABIERTOS DE VACAS HOLSTEIN EN EL DEPARTAMENTO DE ANTIOQUIA, COLOMBIA %A Corrales-¨¢lvarez %A Juan D. %A Cer¨®n-Mu£¿oz %A Mario F. %A Ca£¿as-¨¢lvarez %A Jhon J. %A Acevedo-Valladarez %A Cristina %A Sep¨²lveda-Restrepo %A Jeannie C. %A Calvo-Cardona %A Samir J. %A Moreno-Ochoa %A Manuel %J Actualidades Biol¨®gicas %D 2010 %I Universidad de Antioquia %X the aim of this study was to determine allele and phenotypic frequencies for single nucleotide polymorphism (snp) of exon vi in the pit-1 gene and their associations with type traits, milk yield, and days open. a total of 390 holstein cows from antioquia (colombia) were genotyped for the pit-1 hinfi polymorphism by pcr-rflp. we found aa, ab, and bb genotypes with a frequency of 0.03, 0.43, and 0.53, respectively. the a allele frequency was 0.35 and its presence in the genotype was associated with higher milk production, udder depth and body depth; the absence of the a allele in the genotype was associated with fewer days open. this study indicates that it is possible to develop breeding programs using the pit-1 gene in holstein cattle in the department of antioquia. %K animal breeding %K colombia %K holstein cows %K molecular marker %K pit-1. %U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0304-35842010000200002&lng=en&nrm=iso&tlng=en