%0 Journal Article
%T Uso do infliximab na consulta de gastrenterologia pedi¨¢trica
%A Marques
%A Rita
%A Caldeira
%A Filipa
%A Costa
%A Cl¨¢udia
%A Cunha
%A Jos¨¦ da
%A Ferreira
%A Maria Gomes
%J Jornal Portugu¨ºs de Gastrenterologia
%D 2012
%I Sociedade Portuguesa de Gastrenterologia
%X introduction: infliximab is a monoclonal antibody used in refractory inflammatory bowel disease (ibd). aim: to evaluate the clinical response and adverse effects of infliximab therapy in paediatric ibd patients. methods: analytic, descriptive and cross sectional study of outpatient clinic of pediatric gastroenterology treated with infliximab. results: of six patients treated with infliximab, five have moderate to severe crohn¡¯s disease and one present ulcerative colitis. there was clinical remission in five patients. resolution in analytical changes was observed after 6 months of therapy. there were two mild allergic reactions and a transient elevation of transaminases. conclusions: in accordance with the literature, in our population, infliximab therapy has been well tolerated and effective in disease control.
%K infliximab
%K inflammatory bowel disease
%K pediatric.
%U http://www.scielo.gpeari.mctes.pt/scielo.php?script=sci_abstract&pid=S0872-81782012000300004&lng=en&nrm=iso&tlng=en