%0 Journal Article
%T Efecto en el sangrado perioperatorio durante la resecci¨®n transuretral de la pr¨®stata tras un mes de tratamiento con dutasteride
%A Arratia-Maqueo
%A J.A.
%A Garza-Cort¨¦s
%A R.
%A G¨®mez-Guerra
%A L.S.
%A Cort¨¦s-Gonz¨¢lez
%A J.R.
%J Actas Urol¨®gicas Espa£¿olas
%D 2010
%I Scientific Electronic Library Online
%R 10.4321/S0210-48062010001000009
%X objective: evaluate the effect of dutasteride in perioperative bleeding during transurethral resection of prostate (turp). materials and methods: forty consecutive patients with criteria for turp were included. finasteride/dutasteride use, renal impairment, prostate <30cc, age <50 were excluded. patients were divided in 2 groups. group 1: 24 consecutive patients treated with dutasteride 0.5mg/day/30-days prior turp. group 2: 16 without treatment. prostatic volume, difference in hemoglobin pre/post turp, duration and amount of resected tissue were recorded. surgeon was blinded. statistical analysis: multiple linear regression, mann-whitney and student t-tests were used. results: in group 1, 33%(8) improved their lower urinary tract symptoms and skipped turp. mean hemoglobin loss difference between groups was 0.11gr/dl (ci 95% -0.55; 0.77, p=0.88). there was no statistical difference among variables. no positive or negative predictive values in the linear regression model. conclusion: dutasteride did not significantly impact the studied variables in these non randomized and small sample size settings.
%K benign prostatic hyperplasia
%K hematuria
%K finasteride
%K transurethral resection of the prostate
%K dutasteride.
%U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0210-48062010001000009&lng=en&nrm=iso&tlng=en