%0 Journal Article
%T Relaci¨®n entre los niveles plasm¨¢ticos de selenio y las diferentes enfermedades prost¨¢ticas
%A L¨®pez Fontana
%A C.M.
%A P¨¦rez Elizalde
%A R.F.
%A Vanrell
%A M.C.M.
%A Recalde
%A G.M.
%A Uvilla
%A A.L.
%A L¨®pez Laur
%A J.D.
%J Actas Urol¨®gicas Espa£¿olas
%D 2010
%I Scientific Electronic Library Online
%R 10.4321/S0210-48062010000700009
%X several studies have demonstrated an inverse relation between serum selenium levels (se) and advanced prostate cancer (pca). objective: to determine and compare selenium plasma levels in patients with different prostatic pathologies. material and methods: it is a transversal, descriptive and comparative study. a sample of 64 men between 50 and 80 years old were selected for the study between 2007 and 2009. all volunteers underwent a digital rectal examination, prostate specific antigen level, ultrasound and transrectal prostate biopsy (12-14 chips). prostate cancer was subclassified according to gleason score. selenium was determined indirectly by serum glutathione peroxidase (kit ransel, randox srl, crumlin, uk). statistical analysis was performed using anova i (p<0.05). results: glutathione peroxidase level was 33.75¡À2.36mg/ml in control patients. a decrease of 31.6% was observed in patients with bph (23.08¡À1.57mg/ml) and of (63.6%) in subjects with prostate cancer (12.28¡À1.03mg/ml) (p<0,0001). there was no correlation with the gleason score. conclusion: serum seleniun is lower in patients with prostatic pathologies being even more important in cancer patients regardless the gleason score.
%K selenium
%K prostate cancer
%K benign prostatic hyperplasia
%K chronic prostatitis.
%U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0210-48062010000700009&lng=en&nrm=iso&tlng=en