%0 Journal Article
%T Tratamento da disforia pr¨¦-menstrual com antidepressivos: revis£¿o dos ensaios cl¨ªnicos controlados
%A Cheniaux
%A Elie
%J Jornal Brasileiro de Psiquiatria
%D 2006
%I Universidade Federal do Rio de Janeiro
%R 10.1590/S0047-20852006000200008
%X intoduction: premenstrual dysphoria (pmd), which affects between 3% and 8% of women during reproductive years, represents a more severe type of premenstrual syndrome. mood and behavior changes are predominant in pmd. it is believed that there is some kind of link between pms and mood disorders. objective: studying the efficacy of antidepressants in pmd. methods: we elaborated a review of controlled clinical trials with antidepressants in the treatment of pmd, using the following databases: medline, lilacs, psycinfo and cochrane library. results: clomipramine, fluoxetine, sertraline, paroxetine and venlafaxine were superior to placebo in various studies. discussion: women with pmd possibly present a serotonergic dysfunction. conclusion: some antidepressants, specialy ssris, seem to be effective in the treatment of pmd.
%K premenstrual syndrome
%K treatment
%K antidepressants
%K review.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0047-20852006000200008&lng=en&nrm=iso&tlng=en