%0 Journal Article %T Physical map and one-megabase sequencing of the human immunoglobulin lambda locus %A Passos Jr. %A Geraldo A.S. %J Genetics and Molecular Biology %D 1998 %I Sociedade Brasileira de Gen¨¦tica %R 10.1590/S1415-47571998000200019 %X the human immunoglobulin lambda (igl) locus is located on chromosome 22q11.1-q11.2 and contains the genes responsible for the immunoglobulin lambda light chains. this locus was recently mapped (physical map) and its 1-mb dna totally sequenced. in this review we focus on the characterization of the v-lambda genes, its chromosomal location, genomics and sequencing of the igl locus. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1415-47571998000200019&lng=en&nrm=iso&tlng=en