%0 Journal Article
%T Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
%A Cambruzzi
%A Eduardo
%A Molinari
%A Alberto Salgueiro
%A Uch£¿a
%A Diego Mendon£¿a
%A Y¨¦pez
%A Vanessa
%J Jornal Brasileiro de Patologia e Medicina Laboratorial
%D 2012
%I Sociedade Brasileira de Patologia Cl¨ªnica
%R 10.1590/S1676-24442012000400009
%X extramedullary plasmacytoma comprises 3%-5% of all plasma cell neoplasms, and approximately 80% of the cases occur in the upper respiratory tract. primary thyroid plasmacytomas (ptp) are rare tumors. the authors report a case of ptp in a male patient with dyspnea and dysphagia. physical examination and computerized tomography (ct) scan revealed a solid tumor affecting the thyroid gland, measuring 12 cm in its greatest dimension. surgical biopsy was performed. microscopy revealed a hypercellular malignant neoplasm composed of round plasmacytoid cells arranged in solid nests, which showed a positive immunoexpression for cd138, epithelial membrane antigen (ame), kappa light chains and multiple myeloma oncogene 1 (mum1). the diagnosis of ptp was accordingly established.
%K plasmacytoma
%K thyroid gland
%K multiple myeloma
%K immunohistochemistry.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1676-24442012000400009&lng=en&nrm=iso&tlng=en