%0 Journal Article
%T Punto de corte 車ptimo de la concentraci車n de cotinina en saliva para discriminar entre fumadores y no fumadores en la poblaci車n adulta de Barcelona
%A Mart赤nez-S芍nchez
%A Jose M.
%A Fu
%A Marcela
%A Ariza
%A Carles
%A L車pez
%A Mar赤a J.
%A Salt車
%A Esteve
%A Pascual
%A Jos谷 A.
%A Schiaffino
%A Anna
%A Borr角s
%A Josep M.
%A Peris
%A Merc豕
%A Agudo
%A Antonio
%A Nebot
%A Manel
%A Fern芍ndez
%A Esteve
%J Gaceta Sanitaria
%D 2009
%I Ediciones Doyma, S.L.
%R 10.1590/S0213-91112009000600003
%X objective: to assess the optimal cut-point for salivary cotinine concentration to identify smoking status in the adult population of barcelona. methods: we performed a cross-sectional study of a representative sample (n=1,117) of the adult population (>16 years) in barcelona (2004-2005). this study gathered information on active and passive smoking by means of a questionnaire and a saliva sample for cotinine determination. we analyzed sensitivity and specificity according to sex, age, smoking status (daily and occasional), and exposure to second-hand smoke at home. roc curves and the area under the curve were calculated. results: the prevalence of smokers (daily and occasional) was 27.8% (95% ci: 25.2-30.4%). the optimal cut-point to discriminate smoking status was 9.2ng/ml (sensitivity=88.7% and specificity=89.0%). the area under the roc curve was 0.952. the optimal cut-point was 12.2ng/ml in men and 7.6ng/ml in women. the optimal cut-point was higher at ages with a greater prevalence of smoking. daily smokers had a higher cut-point than occasional smokers. conclusions: the optimal cut-point to discriminate smoking status in the adult population is 9.2ng/ml, with sensitivities and specificities around 90%. the cut-point was higher in men and in younger people. the cut-point increases with higher prevalence of daily smokers.
%K sensitivity
%K specificity
%K roc curve
%K cotinine
%K cut-off point
%K smoking.
%U http://www.scielosp.org/scielo.php?script=sci_abstract&pid=S0213-91112009000600003&lng=en&nrm=iso&tlng=en