%0 Journal Article
%T Efecto de diferentes variables sociodemogr¨¢ficas en la progresi¨®n de la infecci¨®n por el virus de la inmunodeficiencia humana en una cohorte de usuarios de drogas
%A Hurtado
%A Isabel
%A Hern¨¢ndez-Aguado
%A Ildefonso
%A Ferreros
%A Inmaculada
%A Lumbreras
%A Blanca
%A P¨¦rez-Hoyos
%A Santiago
%J Gaceta Sanitaria
%D 2008
%I Ediciones Doyma, S.L.
%R 10.1590/S0213-91112008000600007
%X objective: to analyze whether the effectiveness of combined antiretroviral therapy in delaying progression to aids and death is affected by social inequities in a cohort of hiv-positive injecting drug users (idus). methods: a cohort of 3,122 hiv-positive idus identified in the aids information and prevention centers of the autonomous region of valencia was analyzed, with further follow-up in 1,876. progression to aids and death after seroconversion were calculated by kaplan-meier estimation according to sociodemographic variables (age, sex, education, marital status, length of addiction). cox regression models were also fitted. results: no significant differences were observed according to the variables considered when analyzing time to aids development. evaluation of survival time revealed that individuals with further follow-up showed an excess of mortality (hr = 1.35; 95%ci: 0.20-1.54). for individuals without follow-up, mortality risk was reduced in those with secondary school education (hr = 0.51; 95%ci: 0.35-0.74) and with university education (hr = 0.41; 95%ci: 0.18-0.93) compared with those with no education. when individuals with follow-up were analyzed, the differences lost significance for those with secondary school education (hr = 0.92; 95%ci: 0.72-1.19) and university education (hr = 0.62; 95%ci: 0.35-1.11). conclusions: the mortality excess found in idus with lower educational levels, especially among those not seeking healthcare in the initial period after being identified as hiv-positive, highlights the need for interventions aimed at facilitating access to health systems, especially among the socially disadvantaged.
%K hiv
%K death
%K injecting drug users
%K cohort
%K socio-demographic differences.
%U http://www.scielosp.org/scielo.php?script=sci_abstract&pid=S0213-91112008000600007&lng=en&nrm=iso&tlng=en