%0 Journal Article
%T Escorpionismo del g¨¦nero Tityus en la sierra falconiana y su correlaci¨®n con la liberaci¨®n de mediadores inflamatorios y enzimas card¨ªacas
%A Guinand
%A Alejandro
%A Cort¨¦s
%A Hernando
%A D¡äSuze
%A Gina
%A D¨ªaz
%A Patricia
%A Sevcik
%A Carlos
%A Gonz¨¢lez-Sponga
%A Manuel
%A Eduarte
%A Giovanny
%J Gaceta M¨¦dica de Caracas
%D 2004
%I Scientific Electronic Library Online
%X five scorpion species were identified at the falcon state mountain but only tityus falconensis was associated with the cases that developed a systemic symptomatology. in the 15 patients studied we found that venenemia, nitric oxide, interleukin-6, tumor necrosis factor-a and creatinphosphoquinase increased with the severity of the sting. this study reveals the role of scorpion toxins on the activation of the inflammatory response. increases of the creatinphosphoquinase-mb during the first 2 hours after the accident, suggest that t. falconensis content abundant cardiotoxic toxins. we observed that glycemia and amylase were not altered by these venom and 3 of the patients studied showed altered coagulation times.
%K scorpionism
%K venenemia
%K cytokines
%K nitric oxide
%K creatinphosphoquinase-mb.
%U http://www.scielo.org.ve/scielo.php?script=sci_abstract&pid=S0367-47622004000200006&lng=en&nrm=iso&tlng=en