%0 Journal Article %T Determinaci¨®n de Subpoblaciones linfocitarias en lesiones de pacientes con Estomatitis Aftosa Recurrente %A Gutierrez %A R %A Correnti %A M %A Perrone %A M %A De Guglielmo %A Z %J Acta Odontol¨®gica Venezolana %D 2008 %I Scientific Electronic Library Online %X recurrent aphtous stomatitis (ras) is one of the most common oral mucosal diseases known. it presents as threee types: minor (most prevalent), major and herpetiform. however, not thue well established its etiology although, many evidences indicated that the patients affected with this condition have a defectous celular immune response. the objective of this study was the determination of£¿ the lymphocytes subpopulations t cd4+ and t cd8+ in patients with ras. we evaluated 19 patients, 15£¿ with minor ras and 4 with major ras.£¿ as a control group we included 10 patients withouth ras.£¿ we obtained a biopsy of each patient, that was procesed by immunohistochemistry. we observed a very high amount of lymphocytes subpopulations in the patients with ras in comparation with the control group. the results suggested the association£¿ of the t lymphocytes and the the celular immune response in the pathogenesis of the ras %K estomatitis aftosa recurrente %K inmunidad celular. %U http://www.scielo.org.ve/scielo.php?script=sci_abstract&pid=S0001-63652008000200007&lng=en&nrm=iso&tlng=en