%0 Journal Article %T Granuloma Perif¨¦rico de C¨¦lulas Gigantes: Reporte de dos Casos y Revisi¨®n de la Literatura. %A L¨®pez-Labady %A J %A Moret %A Y %A Virguez %A Y %J Acta Odontol¨®gica Venezolana %D 2008 %I Scientific Electronic Library Online %X the peripheral giant cell granuloma (pgcg) is a reactive lesion that originates from periosteum or the periodontal membrane after irritation or chronic local trauma. it appears at any age with important prevalence for female gender. it usually appears as a tumor like lesion, its color ranges from red to purple and it is located on the gingiva. its radiographic pattern could show surface erosion of the underlying bone. under microscope analysis it shows hyperplasic granulation tissue and characters of giant multinucleated cells. in this article are present two cases of pgcg in 2 women (62 and 20 years old) both of them in mandible bone, bicuspids zone, both with similar clinical appearance. these cases were tumor like lesions, red color, bleeding aspect with presence of local irritants the type of calculus and plaque. under radiographic analysis in one of the cases it was determined a bony lesion associated to the pathology of study.£¿ periodontal therapy was selected as treatment before surgical removal of both lesions and respective histopathological study, reporting pgcg as final diagnosis. the early and precise diagnosis of these lesions leads to conservative treatment avoiding risk to neighboring teeth and underlying bone. it is to emphasize the importance of these cases because they state that this pathology does not show prevalence for age range as well as reaffirms its prevalence for female gender. %K granuloma %K peripheral %K giant cell. %U http://www.scielo.org.ve/scielo.php?script=sci_abstract&pid=S0001-63652008000100017&lng=en&nrm=iso&tlng=en