%0 Journal Article
%T Non-cancerous prognostic factors of hepatocellular carcinoma after liver transplantation
%A Batista
%A Thales Paulo
%A Miranda
%A Luiz Eduardo Correia
%A Sabat
%A Bernardo David
%A Melo
%A Paulo S¨¦rgio Vieira de
%A Fonseca Neto
%A Olival Cirilo Lucena da
%A Amorim
%A Am¨¦rico Gusm£¿o
%A Lacerda
%A Cl¨¢udio Moura
%J Acta Cirurgica Brasileira
%D 2012
%I Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
%R 10.1590/S0102-86502012000600007
%X purpose: to explore non-cancerous factors that may be related with medium-term survival (24 months) after liver transplantation (lt) in this data from northeast brazil. methods: a cross-sectional study was carried out in patients who underwent deceased-donor orthotopic lt because hepatocellular carcinoma (hcc) at the university of pernambuco, brazil. non-cancerous factors (i.e.: donor-, receptor-, surgery- and center-related variables) were explored as prognostic factors of medium-term survival using univariate and multivariate approachs. results: sixty-one patients were included for analysis. their three, six, 12 and 24-month overall cumulative survivals were 88.5%, 80.3%, 73.8% and 65.6%, respectively. our univariate analysis identified red blood cell transfusion (exp[b]=1.26; p<0.01) and hepato-venous reconstruction technique (84.6% vs. 51.4%, p<0.01; respectively for piggyback and conventional approaches) as significantly related to post-lt survival. the multivariate analysis confirmed the hepato-venous reconstruction technique was an independent prognostic factor. conclusion: the piggyback technique was related to improved medium-term survival of hepatocellular carcinoma patients after liver transplantation in this northeast brazilian sample.
%K organ transplantation
%K liver neoplasms
%K carcinoma
%K hepatocellular
%K survival analysis
%K prognosis.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0102-86502012000600007&lng=en&nrm=iso&tlng=en