%0 Journal Article
%T Testosterona, emoci¨Žn y cognici¨Žn: Estudios en animales castrados
%A Justel
%A Nadia
%A Bentosela
%A Mariana
%A Ruetti
%A Eliana
%J Interdisciplinaria
%D 2010
%I Scientific Electronic Library Online
%X sexual behavior is a very important part in the life of animals, and sexual hormones, such as estrogen in females and testosterone in males, regulate the behavior of most mammals. testosterone, the male sexual hormone, plays an important role in the development of the brain organization necessary for sexual behavior. some evidences show that testosterone affects animal behavior and has an anxiolytic as well as analgesic effects on the behavior of rats, mice, dogs, and humans. for example, men who have higher endogenous levels of testosterone have a lower incidence of depression. conversely, young hypogonad men, with low endogenous testosterone, are more likely to be diagnosed with anxiety or depressive disorders, and exhibit decreased performance in some cognitive tasks. in animal models of androgen deficiency, androgens can mediate both, affective and cognitive behavior. removing rats primary source of endogenous androgens through androgen extirpation (i.e., castration or gonadectomy) results in increased anxiety-like behavior, and detriments in cognitive performance. in the present paper, we review the main research on the effect of sexual hormone depletion, through gonadectomy, on the behavior of adult male rats. there are different ways to study the influence of testosterone on emotion and cognition, the study of the sexual behavior, the study of the administration of testosterone and their metabolites and the effect of the depletion of testosterone. this review is arranged in two main sections: on the one hand, we describe studies about castration effects on animal emotion; on the other hand, we discuss most relevant contributions linked to the effect of testosterone depletion on cognition. to finish, there is a section where we explain the neurobiological mechanisms involved in emotion and cognition of animals with hormone depletion. data suggests that testosterone modulates emotion, in particular anxiety, fear, pain, and depression responses. results from dif
%K testosterone
%K emotion
%K cognition
%K castration.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S1668-70272010000200001&lng=en&nrm=iso&tlng=en