%0 Journal Article
%T Predictors of Mortality in Neonates with Congenital Anterior Abdominal Wall Defects: A Twelve-Year Review of Records in a Tertiary Health Centre
%A Andrew Haruna Shitta
%A Ezekiel Dido Dung
%A Solomon Danjuma Peter
%A Daanan Joseph Shilong
%A Linus Anthony
%A Uche Agwu Arua
%A Victor Ibukun Imade
%A Elijah Danladi Wuyep
%A Godwin Oko Adariku
%A Abraham Isha Ashom
%A Mercy Wakili Isichei
%A Francis Aba Uba
%A Lofha Bali Chirdan
%J Open Journal of Pediatrics
%P 517-527
%@ 2160-8776
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojped.2025.154049
%X <b>Background:</b> Anterior abdominal wall defect is a spectrum of congenital malformations arising from defective fusion or development of the embryonic folds. Gastroschisis and omphalocele constitute the majority of cases. <b>Methods:</b> A retrospective study of newborns with anterior abdominal wall defects at our facility from February 2012 to June 2023. <b>Results:</b> A Total of 142 newborns presented with anterior abdominal wall defects. Females 74 and males 68, ratio of 0.9:1. Median age at presentation was 18.5 hours. Mean birth weight was 2.6 &#177; 0.6 kg, range of 1.1 kg - 4.2 kg. There were 120 (83.8%) newborns with omphalocele, 14 (9.9%) with gastroschisis, prune belly 3 (2.1%), bladder exstrophy, cloacal exstrophy, a set of conjoined twins and pentalogy of Cantrell 1 (0.7%) each. Of the 120 with omphalocele, 107 were omphalocele major, 13 omphalocele minor while 45 (37.5%) presented with ruptured membrane. Complication: sepsis (38, 26.7%). Length of hospital stay 0.2 days - 63 days, mean of 15 days. Mortality 62 (43.7%), treated and discharged home 80 (56.3%). Of the 62 mortalities, 45 (72.6%) occurred in week one. Case fatality rate: pentalogy of Cantrell 1(100%), Gastroschisis 13 (92.85%) and omphalocele major 44 (41.1%). Of the 44 mortalities with omphalocele major, 26 (51.1%) had ruptured membranes. Logistic regression: birth weight (OR = 0.209, CI = 0.083 - 0.525, p = 0.001); Duration of hospital stay (OR = 0.287, CI = 0.287 - 9.985, p &lt; 0.001) and type of defect (OR = 0.449, CI = 0.276 - 0.731, p = 0.001) significantly predicted mortality. <b>Conclusion</b><b>:</b> Low birth weight and type of defect (ruptured omphalocele and gastroschisis) were significant predictors of mortality.
%K Predictors
%K Mortality
%K Neonates
%K Abdominal-Wall
%K Defects
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=143982