%0 Journal Article
%T Follow-Up of HPV Clearance after LEEP Conization and Vaporization for CIN2<sup>+</sup>, and Vaporization for VaIN2
%A Kenji Niwa
%A Saki Tsurue
%A Rui Kyogoku
%A Masanori Isobe
%A Yoh Hayasaki
%A Sakae Mori
%A Keigo Kuwabara
%A Kentaro Niwa
%A Takuji Tanaka
%J Open Journal of Pathology
%P 136-149
%@ 2164-6783
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojpathology.2025.153013
%X LEEP conization with vaporization was performed for 86 CIN2<sup>+</sup> cases. Our data suggest that combining LEEP conization and vaporization results in a higher estimated cumulative HPV clearance rate than LEEP alone. The clearance rate tended to be better in younger patients. Vaporization could provide a promising therapeutic option for VaIN2 associated with high-risk HPV infection. Treatment of CIN2<sup>+</sup> and VaIN2 using ball electrode vaporization and LEEP conization appears feasible and effective, even in settings lacking specialized surgical devices. After conservative treatment of CINs or VaIN, HR-HPV persists in some cases even in the NILM state without dysplasia, and long-term follow-up is needed.
%K HPV
%K CINs
%K LEEP Conization
%K Vaporization
%K VaIN
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=143891