%0 Journal Article
%T Factors Associated with Dyslipidemia in Adults with Chronic Kidney Disease at the Borgou Teaching Hospital (Benin)
%A S&#233
%A raphin Ahoui
%A Carole Djessou
%A Evariste Eteka
%A Nicanor S. Houeto
%A Hermione N. Djima
%A Aim&#233
%A Vinasse
%A Aubin M. Melikan
%A Joseph Godonou
%A Jacques Vigan
%A Moutawakilou Gomina
%J Open Journal of Nephrology
%P 321-333
%@ 2164-2869
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojneph.2025.152030
%X <b>Introduction:</b> Cardiovascular disease (CVD) is very common in chronic kidney disease (CKD). Lipoprotein metabolism is impaired in CKD patients, which is a significant risk factor for atherosclerosis and thus CVD. <b>Objective:</b> To investigate the serum lipid profile of patients with chronic kidney disease at CHUD-B/A in 2021. <b>Method:</b> A cross-sectional, descriptive and analytical study was conducted from January 2 to June 30, 2021, at the CHUD-B/A, in adult patients with CKD received in consultation or hospitalized. After ethical consultation, a venous blood sample was taken, followed by the determination of lipid parameters (total cholesterol, HDL cholesterol, triglycerides) by enzymatic colorimetric methods. LDL-cholesterol was calculated according to the formula of Friedwald <i>et al.</i> The plasma atherogenic index (PAI) was obtained by the formula log (triglycerides/HDL-cholesterol). Dyslipidemias was defined according to the <i>National Cholesterol Education Program Adult Treatment Pane</i><i>l III </i>(<i>NCEP/ATP III</i>) classification. Logistic regression was used to identify factors associated with dyslipidemia at the 5% level. <b>Results:</b> A total of 54 patients with CKD were enrolled. The hospital prevalence of dyslipidemia was 64.81%. The different types of dyslipidemia found were HDL hypocholesterolemia (40.74%), LDL hypercholesterolemia (33.33%), hypertriglyceridemia (29.63%), total hypercholesterolemia (24.07%), mixed hyperlipidemia (12.96%), atherogenic dyslipidemia (7.41%). High PAI was the most common with 64.81%. Abdominal obesity was associated with mixed hyperlipidemia (p = 0.0043). HDL hypocholesterolemia was associated with end-stage CKD (p = 0.0001). Obesity (BMI) was a risk factor for LDL hypercholesterolemia (p = 0.0082). <b>Conclusion: </b>The hospital prevalence of dyslipidemia is high in patients with CKD. Serum lipid parameters should be included in the follow-up consultations of CKD patients.
%K Dyslipidemia
%K Atherogenic Plasma Index
%K Chronic Kidney Disease
%K Benin
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=143612