%0 Journal Article
%T Association Between Hypoalbuminemia and Mortality in Critically Ill Non-Surgical Adult Patients: A Systematic Review and Meta-Analysis
%A Jackson Rashid Djuma
%A Eva Tshaba Kashinda
%A Serge Kapend Matanda
%A Pascaline Migabo
%A Olivier Bwemere
%A Beros Vangu
%A Assa Eca Kreedom
%A Michel Manika
%A Christian Ngandu
%A Claudine Malonga
%A Deogratias Mulungulungu
%A Hassane Njimi
%A Jean Charles Preiser
%J Open Journal of Emergency Medicine
%P 178-195
%@ 2332-1814
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojem.2025.132017
%X <b>Purpose</b>: The aim of this meta-analysis was to assess if hypoalbuminemia can predict mortality in critically ill non-surgical adult patients. <b>Methods</b>: We searched on Public Access to Medline (PubMed), Europe PubMed Central (Europe PMC) and ScienceDirect databases for relevant articles published from 1 January 2018 to 31 December 2024. We included observational studies of critically ill non-surgical adult patients in European hospitals. We performed the meta-analysis on Review Manager (RevMan Web by Cochrane Collaboration). The adjusted Odds Ratio (OR) for the association between hypoalbuminemia and mortality was extracted from included articles and pooled with 95% confidence intervals (CI). A random effect model was used. Sensitivity analysis was performed on RevMan. <b>Results:</b> We included a total of 9 observational studies with 6846 participants. Hypoalbuminemia was significantly associated with high mortality among critically ill non-surgical adult patients. The pooled OR was: 1.93 95% CI: 1.45, 2.56. Heterogeneity (I<sup>2</sup>) = 93% P &lt; 0.00001. Sensitivity analysis showed that no study had an undue influence on the results of the study, as the effect size remained statistically significant to the exclusion of any study. <b>Conclusion: </b>The meta-analysis found that Hypoalbuminemia is a significant predictor of mortality for critically ill non-surgical adult patients. Our results may suggest that great attention should be paid for critically ill non-surgical adult patients with hypoalbuminemia to reduce the bad outcome. Health policies and procedures should include the albumin test for better outcomes.
%K Hypoalbuminemia
%K Mortality
%K Severe Non-Surgical Adult Patients
%K Meta-Analysis
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=143605