%0 Journal Article
%T EB病毒与肺部疾病关系的研究进展
Research Progress on the Relationship between EB Virus and Pulmonary Diseases
%A 吕品田
%A 山凤连
%J Journal of Clinical Personalized Medicine
%P 614-619
%@ 2334-3443
%D 2025
%I Hans Publishing
%R 10.12677/jcpm.2025.43387
%X EB病毒是一种传染性病毒，能够引起多种原发感染，导致并发症，并诱发各种恶性肿瘤，给人们的生命健康带来极大威胁。1964年Epstein和Barr在非洲儿童恶性淋巴瘤的细胞培养物中发现了EB病毒，其发现标志着人类疱疹病毒研究领域的重要突破。此病毒广泛存在于人群中，大部分感染者无明显症状，少数成人感染可表现为传染性单核细胞增多症。然而越来越多的研究证明EB病毒与呼吸系统疾病也存在关联，影响多种呼吸系统疾病的发生、发展，影响疾病的预后，与病情程度密切相关。本文旨在对肺部疾病与EB病毒关系的研究进展进行综述，详细阐述EB病毒的感染机制、影像学，深入探讨其与慢性阻塞性肺疾病、肺癌、肺炎等常见肺部疾病的相关性以及治疗和预后，并对未来的研究方向进行展望，旨在提高人们对EB病毒导致肺部疾病的认识，为肺部疾病的临床诊断、治疗及预防提供新的思路和理论依据。
Epstein-Barr (EB) virus is a contagious virus that can cause a variety of primary infections, leading to complications and inducing various malignant tumors, posing a significant threat to human health. In 1964, Epstein and Barr discovered EB virus in cell cultures of African children with malignant lymphoma, marking a significant breakthrough in the field of human herpesvirus research. This virus is widely present in the human population, with most infected individuals showing no obvious symptoms. However, a minority of adult infections may manifest as infectious mononucleosis. Increasing evidence has shown that EB virus is also associated with respiratory diseases, influencing the occurrence, development, prognosis, and severity of various respiratory conditions. This review aims to summarize the research progress on the relationship between pulmonary diseases and EB virus, elaborating on the infection mechanisms and imaging characteristics of EB virus, and exploring its associations with common pulmonary diseases such as chronic obstructive pulmonary disease (COPD), lung cancer, and pneumonia, as well as treatment and prognosis. Future research directions are also discussed, with the goal of enhancing the understanding of pulmonary diseases caused by EB virus and providing new insights and theoretical foundations for the clinical diagnosis, treatment, and prevention of pulmonary diseases.
%K EB病毒，
%K 肺部疾病，
%K 肺炎，
%K 慢性阻塞性肺疾病，
%K 肺癌，
%K 综述
EB Virus
%K Pulmonary Disease
%K Pneumonia
%K Chronic Obstructive Pulmonary Disease
%K Lung Cancer
%K Review
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=117286