%0 Journal Article
%T Therapeutic Compliance in Patients Followed for Lupus and Rheumatoid Arthritis in Niamey (Niger): Multicenter Study
%A Brah Souleymane
%A Daou Mamane
%A Hamsatou Almoustapha
%A Andia Abdoulkader
%A Abdoul Aziz Garba
%A Alkassoum Ibrahim Salifou
%A Adehossi Eric
%J Open Journal of Internal Medicine
%P 151-162
%@ 2162-5980
%D 2025
%I Scientific Research Publishing
%R 10.4236/ojim.2025.152014
%X <b>Introduction:</b> Like all chronic diseases, Autoimmune diseases (AID) require long-term, even lifelong, medication. Their progression and prognosis depend on adherence to these therapies, which are often fraught with side effects. We conducted a study on the adherence of patients being treated for systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). <b>Method</b><b>:</b> Our study was prospective, descriptive and analytical, lasting 3 months from May 20, 2024, to August 20, 2024, in the 3 reference hospitals of Niamey. <b>Results</b><b>:</b> A total of 27 patients were included, representing 30% of the patients with lupus and/or rheumatoid arthritis collected. The age group over 35 years was the most represented, with a frequency of 74.1% (n = 20) and a female predominance of 92.60% (n = 25). Prednisone and hydroxychloroquine were the most used molecules, 70.4% each, followed by methotrexate at 22.2%. Low adherence predominated, followed by medium adherence and high adherence in 67% (n = 18), 26% (n = 7) and 7% (n = 2) respectively. Adherence to antimalarials was the lowest, followed by glucocorticoids and immunosuppressants in 51.9% (n = 14), 48.1% (n = 13) and 25.9% (n = 7). Patients with SLE had lower adherence at 44.4% (n = 12). The major barriers to treatment adherence reported by our patients were weariness, forgetfulness, fear of side effects and low socioeconomic level in 51.9% (n = 14), 48.1% (n = 13), 40.7% (n = 11) and 29.6% (n = 8), respectively. <b>Conclusion</b><b>:</b> It is important that physicians adopt a prescribing strategy that focuses on limiting themselves to the essentials, prioritizing single-dose molecules and fixed combinations if necessary.
%K Therapeutic Compliance
%K Lupus
%K Polyarthritis
%K Niger
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=143306