%0 Journal Article
%T 黄芪建中汤治疗胃食管反流病脾胃虚寒证的作用机制及研究进展<br>Mechanism of Action of Huangqi Jianzhong Tang in the Treatment of Gastroesophageal Reflux Disease with Spleen and Stomach Cold Deficiency and Research Progress
%A 闫萌
%A 刘派
%A 何磊
%A 胡雅婷
%A 郭雨昕
%A 钱占红
%J Traditional Chinese Medicine
%P 2057-2064
%@ 2166-6059
%D 2025
%I Hans Publishing
%R 10.12677/tcm.2025.145306
%X 胃食管反流病(GERD)是一种慢性消化系统疾病&#65292;主要临床症状包括反酸、烧心和胸痛。西医治疗主要依赖于抑制胃酸分泌和促进胃肠动力的药物&#65292;旨在改善患者的症状&#65292;甚至治愈GERD。中医理论认为&#65292;GERD脾胃虚寒证的主要病机是中焦虚寒、胃失和降、气逆上冲。黄芪建中汤是《金匮要略》中的经典方剂&#65292;是治疗GERD脾胃虚寒证的常用经方。中医在临床上单独运用黄芪建中汤或联合西药治疗GERD脾胃虚寒证&#65292;可以减轻患者的症状&#65292;提升患者的生活质量。本文探讨了GERD以及黄芪建中汤的中医理论知识&#65292;分析了黄芪建中汤在治疗GERD脾胃虚寒证方面的临床应用和药理作用。对国内当前使用黄芪建中汤治疗GERD脾胃虚寒证的状况进行了论述。目的在于深入理解黄芪建中汤治疗GERD脾胃虚寒证的理论依据&#65292;期望为进一步探索黄芪建中汤治疗GERD脾胃虚寒证的临床实践和基础研究提供参考。<br>Gastroesophageal reflux disease (GERD) is a chronic digestive disorder with major clinical symptoms including acid reflux, heartburn and chest pain. Western medical treatment mainly relies on drugs that inhibit gastric acid secretion and promote gastrointestinal motility, aiming to improve the patient&#8217;s symptoms or even cure GERD. According to Chinese medicine theory, the main pathogenesis of the spleen-stomach deficiency-cold syndrome of GERD is the deficiency of coldness in the middle jiao, loss of gastric harmony, and the reversal of the upward flow of qi. Huangqi Jianzhong Decoction is a classic formula in &#8220;The Essentials of the Golden Chamber&#8221;, which is a commonly used sutra formula for treating spleen-stomach deficiency-cold syndrome of GERD. Traditional Chinese medicine (TCM) practitioners use Huangqi Jianzhong Decoction alone or in combination with western medicines to treat GERD spleen-stomach deficiency-cold syndrome, which can alleviate patients&#8217; symptoms and improve their quality of life. This article discusses GERD and the theoretical knowledge of Chinese medicine in Huangqi Jianzhong Decoction, and analyzes the clinical application and pharmacological effects of Huangqi Jianzhong Decoction in the treatment of GERD. The current status of using Huangqi Jianzhong Decoction for GERD in China is discussed. The aim was to gain a deeper understanding of the theoretical basis of Huangqi Jianzhong Decoction for the treatment of GERD, with the expectation that it would provide a reference for further exploration of the clinical practice and basic research of Huangqi Jianzhong Decoction for the treatment of GERD.
%K 黄芪建中汤&#65292
%K 脾胃虚寒&#65292
%K 胃食管反流病&#65292
%K 作用机制<br>Huangqi Jianzhong Decoction
%K Spleen-Stomach Deficiency-Cold Syndrome
%K Gastroesophageal Reflux Disease
%K Mechanism of Action
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=115084