%0 Journal Article
%T 特发性肺纤维化的发病机制研究进展
Research Progress on the Pathogenesis of Idiopathic Pulmonary Fibrosis
%A 冉鹏
%A 杨华
%J Advances in Clinical Medicine
%P 1-6
%@ 2161-8720
%D 2025
%I Hans Publishing
%R 10.12677/acm.2025.1551335
%X 特发性肺纤维化(IPF)是一种严重威胁人类健康的肺部疾病,其病程呈渐进性发展,最终可能导致患者死亡,这种疾病属于间质性肺炎的一种,其病理特征主要表现为肺部成纤维病灶的形成和肺组织的异常重塑。遗憾的是,目前对于特发性肺纤维化的病因尚无明确认识,这使得其成为临床治疗中的一大难题。病因不明不仅限制了治疗手段的选择,也使得患者无法得到针对性的治疗,从而影响了治疗效果。本文以期通过揭示特发性肺纤维化发病机制之间的内在联系,为IPF的发病机制及诊疗研究提供一些有益的启示和参考。
Idiopathic pulmonary fibrosis (IPF) is a lung disease that seriously threatens human health. Its course of disease is progressive and may eventually lead to death. This disease is a type of interstitial pneumonia. Its pathological features are mainly the formation of pulmonary fibroblast lesions and abnormal remodeling of lung tissue. Unfortunately, there is no clear understanding of the etiology of idiopathic pulmonary fibrosis, which makes it a major problem in clinical treatment. The unknown etiology not only limits the choice of treatment, but also makes it impossible for patients to get targeted treatment, thus affecting the treatment effect. This article aims to provide some useful inspiration and reference for the pathogenesis, diagnosis and treatment of IPF by revealing the internal relationship between the pathogenesis of idiopathic pulmonary fibrosis.
%K 特发性肺纤维化,
%K 发病机制,
%K 细胞
Idiopathic Pulmonary Fibrosis
%K Pathogenesis
%K Cell
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=113641