%0 Journal Article %T Profile of Parkinson¡¯s Patients with Major Cognitive Deficits Received for Consultation at the Ibrahima Pierre Ndiaye Neuroscience Clinic at the CHNU de Fann in 2022 %A Adoum Hamad Zenal Abidine %A Soumaila Boubacar %A Carlos Othon Guelngar %A Kadji Juste Milman %A Kamadore Toure %J Open Access Library Journal %V 12 %N 6 %P 1-7 %@ 2333-9721 %D 2025 %I Open Access Library %R 10.4236/oalib.1113539 %X Introduction: Major cognitive deficits are common in Parkinson¡¯s disease, especially in the advanced stages. The objective of this study was to determine the profile of Parkinson¡¯s patients with major cognitive deficits seen at the Neurosciences Clinic. Patients and Methods: This is a 3-month cross-sectional study (March-June 2022). Parkinson¡¯s patients meeting the MDS (Movement Disorder Society) criteria were included in the study. They underwent a neuropsychological assessment (Senegal Test score ¡Ü 28/39) and ADL assessment (Keur Madiabel Test score ¡Ü 5/6), considered to have a major cognitive deficit according to DSM5. Results: We identified 257 patients, 56 of whom presented with major cognitive impairment, representing a frequency of 21.7% and an adjusted frequency of 23.3%. They were predominantly male (46 cases, or 82%). The mean age was 74.6 ¡À 15 years. The age group of 60 - 80 years was the most affected. Shopkeepers (46%) were the most represented. Hypertension was found in (46%) of cases. The mode of onset was progressive (93%). Executive/visuospatial functions (66.1%) and memory (37.5%) were the most impaired cognitive domains. All patients were on L-Dopa to treat motor symptoms. Conclusion: The assessment of Parkinson¡¯s patients with the Senegal Test and the Keur Madiabel Test is of value in the management of major cognitive deficits. %K Parkinson¡¯s Disease %K Major Cognitive Deficits %K Senegal Test %K Keur Madiabel Test %K Senegal %U http://www.oalib.com/paper/6861073