%0 Journal Article
%T 子痫前期发病机制及潜在生物标志物的研究进展<br>Advances in the Pathogenesis and Potential Biomarkers of Preeclampsia
%A 王雅纯
%A 张润学
%A 周靖雅
%A 韩照照
%A 霍琰
%J Advances in Clinical Medicine
%P 2795-2804
%@ 2161-8720
%D 2025
%I Hans Publishing
%R 10.12677/acm.2025.1541242
%X 子痫前期(Preeclampsia, PE)是以高血压和蛋白尿为主要表现的妊娠期特有的疾病&#65292;治疗不及时常严重危害母儿健康&#65292;目前最有效的治疗措施仅为终止妊娠。PE的发病机制仍未阐明&#65292;随着研究的不断深入&#65292;目前普遍认为其发病是一种多因素、多机制、多通路参与的过程。本文对近期关于PE的定义、分类、发病机制及其相关潜在生物标志物的最新研究进展进行综述&#65292;以期深化对PE的认识&#65292;并为临床筛查、预防及治疗提供理论依据。<br>Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and proteinuria, which poses significant risks to maternal and fetal health if not promptly treated. Currently, the most effective intervention remains the termination of pregnancy. The pathogenesis of preeclampsia remains incompletely understood, but emerging evidence suggests that it involves a multifactorial, multi-mechanism, and multi-pathway process. This review summarizes recent advances in the definition, classification, pathogenesis, and potential biomarkers of preeclampsia, aiming to enhance the understanding of this condition and provide a theoretical foundation for clinical screening, prevention, and treatment strategies.
%K 子痫前期&#65292
%K 发病机制&#65292
%K 生物标志物&#65292
%K 综述<br>Preeclampsia
%K Pathogenesis
%K Biomarker
%K Review
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=112577